Coefficient of inbreeding and Cyrillic to text

About these programs

Coefficient of inbreeding

This program calculates the probability (p) that a selected child in a consanguineous pedigree is autozygous for an allele inherited from an individual in the pedigree who is a common ancestor of both of the child's parents.

The program also calculates the F (coefficient of inbreeding) and R (coefficient of relationship) for the child.

It must be noted that the program assumes that the founder individuals in the pedigree are not themselves inbred. It should also be noted that individuals in the pedigree may be related via common ancestors not shown in the pedigree. These assumptions are in reality most likely false for pedigrees from isolated (physically or socially) populations or cultures that have practiced customary consanguineous marriages over many generations. The calculated values should therefore be regarded as lower limits for the true values of P, F and R.

This program can be obtained from here and the instructions can be found by running the program and selecting 'Menu' > 'Instructions' from the help men, while sample files can be created via the 'Help' > 'Sample data' menu.

A web interface with reduced functionaltiy for this programe can be found here.

Cyrillic to text

This program is designed to create pedigree data files for CoefficientOfInbreeding.exe from Cyrillic 'fam' data files. This program has only been used on files containing no genotype data.

This program can be obtained from here and the instructions can be seen when the program is run.